Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency

@article{Munier2005CharacterizationOT,
  title={Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency},
  author={Sandie Munier and Delphine Delcroix-Gen{\^e}te and La{\"e}titia Carthag{\'e}na and Audrey Gumez and Uriel Hazan},
  journal={Retrovirology},
  year={2005},
  volume={2},
  pages={73 - 73}
}
The persistence of latent HIV-1 reservoirs is the principal barrier preventing the eradication of HIV-1 infection in patients by current antiretroviral therapy. It is thus crucial to understand the molecular mechanisms involved in the establishment, maintenance and reactivation of HIV-1 latency. Since chromatin remodeling has been implicated in the transcriptional reactivation of the HIV-1 promoter, we assessed the role of the histone deacetylase inhibitor sodium butyrate (NaB) on two HIV-1… CONTINUE READING
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