Characterization of two aminopeptidases from human liver


Two aminopeptidases from human liver homogenates were partially purified and characterized by subcellular fractionation, chromatographic procedures and susceptibility to inhibitors. The first enzyme is a chloride-dependent aminopeptidase able to hydrolyze lysine and arginine flnaphthylamides (NA), showing no detectable activity on neutral amino-acyl NA. This enzyme is present in the soluble fraction (83%); it is inhibited 68% by 5 mM Co2+, 90% by 5

DOI: 10.1007/BF01972434

Cite this paper

@article{Freitas2005CharacterizationOT, title={Characterization of two aminopeptidases from human liver}, author={Jos{\'e} Oct{\'a}vio Gonçalves de Freitas and Jorge Almeida Guimar{\~a}es and Durval Rosa Borges and Jos{\'e} Leal Prado}, journal={Agents and Actions}, year={2005}, volume={8}, pages={164-164} }