Characterization of tissue-specific LIM domain protein (FHL1C) which is an alternatively spliced isoform of a human LIM-only protein (FHL1).

@article{Ng2001CharacterizationOT,
  title={Characterization of tissue-specific LIM domain protein (FHL1C) which is an alternatively spliced isoform of a human LIM-only protein (FHL1).},
  author={Enders Kwok Wai Ng and S. Mark Lee and H y Li and Sai Ming Ngai and Stephen Kwok-Wing Tsui and Mary Miu Yee Waye and Cheuk Yu Lee and K. P. Fung},
  journal={Journal of cellular biochemistry},
  year={2001},
  volume={82 1},
  pages={1-10}
}
We have cloned and characterized another alternatively spliced isoform of the human four-and-a-half LIM domain protein 1 (FHL1), designated FHL1C. FHL1C contains a single zinc finger and two tandem repeats of LIM domains at the N-terminus followed by a putative RBP-J binding region at the C-terminus. FHL1C shares the same N-terminal two-and-a-half LIM domains with FHL1 but different C-terminal protein sequences. Due to the absence of the exon 4 in FHL1C, there is a frame-shift in the 3' coding… CONTINUE READING

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