Characterization of the yeast HSP60 gene coding for a mitochondrial assembly factor

@article{Reading1989CharacterizationOT,
  title={Characterization of the yeast HSP60 gene coding for a mitochondrial assembly factor},
  author={Donald S. Reading and Richard L. Hallberg and Alan M Myers},
  journal={Nature},
  year={1989},
  volume={337},
  pages={655-659}
}
The hsp60 protein isolated from the protozoan Tetrahymena thermophila is induced in response to heat stress and is a member of an immunologically conserved family represented in Escherichia coli and in mitochondria of plants and animals1,2. We report here the cloning and characterization of a nuclear gene, HSP60, which codes for the hsp60 homologue from the yeast Saccharomyces cerevisiae. Nucleotide sequence analysis revealed that yeast hsp60 is related to the groEL protein of E. coli3–6 and… CONTINUE READING

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