Characterization of the voltage-activated currents in cultured atrial myocytes isolated from the heart of the common oyster Crassostrea gigas.

@article{Pennec2004CharacterizationOT,
  title={Characterization of the voltage-activated currents in cultured atrial myocytes isolated from the heart of the common oyster Crassostrea gigas.},
  author={J. P. Pennec and H{\'e}l{\`e}ne Talarmin and Mika{\"e}l Droguet and Marie-Agn{\`e}s Giroux-Metg{\`e}s and Maxime Gioux and Germaine Dorange},
  journal={The Journal of experimental biology},
  year={2004},
  volume={207 Pt 22},
  pages={3935-44}
}
Using the macro-patch clamp technique, we show that cardiac myocytes isolated from the heart of the oyster Crassostrea gigas possess several types of voltage-activated ionic currents. (1) A classical non-inactivating potassium current of the IK type that is inhibited by tetraethyl ammonium and shows an outward rectification and a slow activation. (2) A potassium current of the IA type that shows rapid activation and inactivation, and is blocked by 4-amino pyridine or preliminary depolarisation… CONTINUE READING
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