Characterization of the velvet regulators in Aspergillus fumigatus.

@article{Park2012CharacterizationOT,
  title={Characterization of the velvet regulators in Aspergillus fumigatus.},
  author={Hee-Soo Park and Ozg{\"u}r Bayram and Gerhard H Braus and Sun Hee Kim and J R Yu},
  journal={Molecular microbiology},
  year={2012},
  volume={86 4},
  pages={937-53}
}
Fungal development and secondary metabolism is intimately associated via activities of the fungi-specific velvet family proteins. Here we characterize the four velvet regulators in the opportunistic human pathogen Aspergillus fumigatus. The deletion of AfuvosA, AfuveA and AfuvelB causes hyperactive asexual development (conidiation) and precocious and elevated accumulation of AfubrlA during developmental progression. Moreover, the absence of AfuvosA, AfuveA or AfuvelB results in the abundant… CONTINUE READING

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Synthetic Biology Center of Global Frontier Project (20110031955) funded by the Ministry of Education, Science and Technology, Korea

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  • Asexual
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Highly Influential
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