Characterization of the spinal nucleus of the bulbocavernosus neuromuscular system in male mice lacking androgen receptor in the nervous system.

@article{Raskin2012CharacterizationOT,
  title={Characterization of the spinal nucleus of the bulbocavernosus neuromuscular system in male mice lacking androgen receptor in the nervous system.},
  author={Kalina Raskin and Clarisse Marie-Luce and Marie Christine Picot and V{\'e}ronique Bernard and Philippe Mailly and H{\'e}l{\`e}ne Hardin-Pouzet and Franco̧is Tronche and Sakina Mhaouty-Kodja},
  journal={Endocrinology},
  year={2012},
  volume={153 7},
  pages={3376-85}
}
Motoneurons in the spinal nucleus of the bulbocavernosus (SNB) and their target bulbocavernosus (BC) and levator ani (LA) muscles play a role in male copulation and fertility. Testosterone (T) induces sexual differentiation of this SNB neuromuscular system during development and maintains its activation in adulthood. In the rat, T-induced effects mostly involve the androgen receptor (AR). However, the role of central AR in T-induced effects remains to be studied with pertinent genetic models… CONTINUE READING