Characterization of the role of collagen network structure and composition in cancer cell migration

Abstract

The geometry of 3D collagen networks is a key factor that influences the behavior of live cells within extra-cellular matrices. This paper presents a method for automatic quantification of the 3D collagen network geometry with fiber resolution in confocal reflection microscopy images. The proposed method is based on a smoothing filter and binarization of… (More)
DOI: 10.1109/EMBC.2015.7320283

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