Characterization of the regulatory regions in the human desmoglein genes encoding the pemphigus foliaceous and pemphigus vulgaris antigens.

@article{Adams1998CharacterizationOT,
  title={Characterization of the regulatory regions in the human desmoglein genes encoding the pemphigus foliaceous and pemphigus vulgaris antigens.},
  author={Michael John Adams and Martin B. Reichel and I A King and Mark D. Marsden and M D Greenwood and Hilary Thirlwell and Joachim Arnemann and Roger S Buxton and Robin R Ali},
  journal={The Biochemical journal},
  year={1998},
  volume={329 ( Pt 1)},
  pages={165-74}
}
The adhesive proteins in the desmosome type of cell junction consist of two members of the cadherin superfamily, the desmogleins and desmocollins. Both desmogleins and desmocollins occur as at least three different isoforms with various patterns of expression. The molecular mechanisms controlling the differential expression of the desmosomal cadherin isoforms are not yet known. We have begun an investigation of desmoglein gene expression by cloning and analysing the promoters of the human genes… CONTINUE READING

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Molecular Biology Intelligence Unit : Molecular Biology of Desmosomes and Hemidesmosomes

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