Characterization of the rat, mouse, and human genes of growth/differentiation factor-15/macrophage inhibiting cytokine-1 (GDF-15/MIC-1).

Abstract

We have isolated the rat, mouse and human genes of a distant member of the TGF-beta superfamily, growth/differentiation factor-15/macrophage inhibiting cytokine-1 (GDF-15/MIC-1) by screening of genomic libraries. All three genes are composed of two exons, and contain one single intron that interrupts the coding sequences at identical positions within the… (More)

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@article{Boettner1999CharacterizationOT, title={Characterization of the rat, mouse, and human genes of growth/differentiation factor-15/macrophage inhibiting cytokine-1 (GDF-15/MIC-1).}, author={Martina Boettner and M Laaff and Barbara Schechinger and Gudrun A Rappold and Klaus Unsicker and Clemens Suter-Crazzolara}, journal={Gene}, year={1999}, volume={237 1}, pages={105-11} }