Characterization of the rat liver membrane proteome using peptide immobilized pH gradient isoelectric focusing.

@article{Chick2008CharacterizationOT,
  title={Characterization of the rat liver membrane proteome using peptide immobilized pH gradient isoelectric focusing.},
  author={J. M. Chick and Paul A Haynes and Mark P. Molloy and Bengt Bjellqvist and Mark S Baker and Alice C L Len},
  journal={Journal of proteome research},
  year={2008},
  volume={7 3},
  pages={1036-45}
}
Membrane proteins are of particular interest in proteomics because of their potential therapeutic utility. Past proteomic approaches used to investigate membrane proteins have only been partially successful at providing a comprehensive analysis due to the inherently hydrophobic nature and low abundance for some of these proteins. Recently, these difficulties have been improved by analyzing membrane protein enriched samples using shotgun proteomics. In addition, the recent application of… CONTINUE READING

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