• DOI:10.1038/366265A0
Corpus ID: 2715056

Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genome

@article{Brenner1993CharacterizationOT,
  title={Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genome},
  author={S. Brenner and G. Elgar and R. Sanford and A. Macrae and B. Venkatesh and S. Aparicio},
  journal={Nature},
  year={1993},
  volume={366},
  pages={265-268}
}

S. Brenner, G. Elgar, +3 authors S. Aparicio

Published 1993

Biology, Medicine

Nature

CLONING and sequencing techniques now allow us to characterize genes directly instead of having to deduce their properties from their effects. This new genetics reaches its apotheosis in the plan to obtain the complete DNA sequence of the human genome, but this is far beyond the capacity of present sequencing methods. Small 'model' genomes, such as those of Escherichia coli (4.7 megabases (Mb)1 and yeast (14 Mb)2, or even those of Caenorhabditis elegans (100 Mb) and Drosophila(165 Mb), are… CONTINUE READING

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