Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genome

@article{Brenner1993CharacterizationOT,
  title={Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genome},
  author={Sydney Brenner and Greg Elgar and R. Sanford and A D Macrae and Byrappa Venkatesh and Samuel Apar{\'i}cio},
  journal={Nature},
  year={1993},
  volume={366},
  pages={265-268}
}
CLONING and sequencing techniques now allow us to characterize genes directly instead of having to deduce their properties from their effects. This new genetics reaches its apotheosis in the plan to obtain the complete DNA sequence of the human genome, but this is far beyond the capacity of present sequencing methods. Small 'model' genomes, such as those of Escherichia coli (4.7 megabases (Mb)1 and yeast (14 Mb)2, or even those of Caenorhabditis elegans (100 Mb) and Drosophila(165 Mb), are… 
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The decode of the compact 73.8-megabase genome of Dimorphilus gyrociliatus, a meiobenthic segmented worm, reveals a conservative route to genome compaction in annelids, reminiscent of that observed in the vertebrate Takifugu rubripes.
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Conservative route to genome compaction in a miniature annelid
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The decode of the compact 73.8 Mb genome of Dimorphilus gyrociliatus, a meiobenthic segmented worm, reveals a conservative route to genome compaction in annelids, reminiscent of that observed in the vertebrate Takifugu rubripes.
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