Characterization of the pseudogenic and genic homologous regions of von Willebrand factor.

@article{Marchetti1991CharacterizationOT,
  title={Characterization of the pseudogenic and genic homologous regions of von Willebrand factor.},
  author={Giovanna Marchetti and P. Patracchini and Stefano Volinia and Vincenzo Aiello and Mario Schiavoni and Nicola Ciavarella and Elisa Calzolari and Christine Schwienbacher and Franca Bernardi},
  journal={British journal of haematology},
  year={1991},
  volume={78 1},
  pages={71-9}
}
The homologous pseudogenic and genic regions of von Willebrand factor (vWF) were studied in DNA from a patient with homozygous deletion of vWF genes and compared with a normal control. This analysis indicates informative restriction patterns for the investigation of restriction fragment length polymorphisms (RFLPs) and gene lesions, and for molecular cloning. A useful new genic XbaI RFLP was found and characterized. A large BgIII fragment of the pseudogenic region was cloned and mapped, and… CONTINUE READING