Characterization of the potent gonadotropin-releasing activity of RF9, a selective antagonist of RF-amide-related peptides and neuropeptide FF receptors: physiological and pharmacological implications.

Abstract

Identification of RF-amide-related peptides (RFRP), as putative mammalian orthologs of the avian gonadotropin-inhibitory hormone, has drawn considerable interest on its potential effects and mechanisms of action in the control of gonadotropin secretion in higher vertebrates. Yet, these analyses have so far relied mostly on indirect approaches, while direct… (More)
DOI: 10.1210/en.2009-1259

Topics

9 Figures and Tables

Cite this paper

@article{Pineda2010CharacterizationOT, title={Characterization of the potent gonadotropin-releasing activity of RF9, a selective antagonist of RF-amide-related peptides and neuropeptide FF receptors: physiological and pharmacological implications.}, author={Roberto Pineda and David Garc{\'i}a-Galiano and Miguel {\'A}ngel S{\'a}nchez-Garrido and M. Romero and Francisco Ru{\'i}z-Pino and Edith Aguilar and Fred A. Dijcks and Marion Blomenr{\"o}hr and Lady Tatiana Pinilla and Paula I. van Noort and Manuel Tena-Sempere}, journal={Endocrinology}, year={2010}, volume={151 4}, pages={1902-13} }