Characterization of the potassium channels involved in EDHF-mediated relaxation in cerebral arteries.

@article{Petersson1997CharacterizationOT,
  title={Characterization of the potassium channels involved in EDHF-mediated relaxation in cerebral arteries.},
  author={J. S. Petersson and Peter M Zygmunt and Edward D H{\"o}gest{\"a}tt},
  journal={British journal of pharmacology},
  year={1997},
  volume={120 7},
  pages={
          1344-50
        }
}
1. In the presence of NG-nitro-L-arginine (L-NOARG, 0.3 mM) and indomethacin (10 microM), the relaxations induced by acetylcholine and the calcium (Ca) ionophore A23187 are considered to be mediated by endothelium-derived hyperpolarizing factor (EDHF) in the guinea-pig basilar artery. 2. Inhibitors of adenosine 5'-triphosphate (ATP)-sensitive potassium (K)-channels (KATP; glibenclamide, 10 microM), voltage-sensitive K-channels (Kv; dendrotoxin-1, 0.1 microM or 4-aminopyridine, 1 mM), small… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 44 CITATIONS

Similar Papers

Loading similar papers…