Characterization of the porcine ACTH receptor with the aid of a monoclonal antibody.

Abstract

Monoclonal antibodies were raised against the ACTH receptor by immunization of BALB1 c mice with porcine adrenal cortex cell membranes. Competition and binding experiments confirmed that one of these antibodies, IV/14/9, reacted with the ACTH receptor in competition with ACTH and caused a definite ACTH-like effect. This antibody was used to characterize the… (More)

Topics

  • Presentations referencing similar topics