Characterization of the novel amplified in breast cancer-1 (NABC1) gene product.

  title={Characterization of the novel amplified in breast cancer-1 (NABC1) gene product.},
  author={Dillon I. Beardsley and David Kowbel and Tamara A Lataxes and Jennifer M Mannino and Hong Xin and Wan-ju Kim and Colin Collins and Kevin Brown},
  journal={Experimental cell research},
  volume={290 2},
Positional cloning of the cancer-associated 20q13.2 amplicon identified two genes that display high mRNA levels in breast tumors and here we report the initial characterization of one of these gene products, designated Novel Amplified in Breast Cancer-1 (NABC1). Analysis of the primary structure of the NABC1 protein uncovered two regions of this protein with a high likelihood of forming coiled-coils and assembly of a mouse NABC1 cDNA showed that this protein is conserved between mouse and man… CONTINUE READING

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