Characterization of the metabolic changes underlying growth factor angiogenic activation: identification of new potential therapeutic targets.

@article{Vizn2009CharacterizationOT,
  title={Characterization of the metabolic changes underlying growth factor angiogenic activation: identification of new potential therapeutic targets.},
  author={Pedro Viz{\'a}n and Susana S{\'a}nchez-Tena and Gema Alcarraz-Viz{\'a}n and Marta Soler and Ramon Messeguer and Maria Dolors Pujol and Wai-Nang Paul Lee and Marta Cascante},
  journal={Carcinogenesis},
  year={2009},
  volume={30 6},
  pages={946-52}
}
Angiogenesis is a fundamental process to normal and abnormal tissue growth and repair, which consists of recruiting endothelial cells toward an angiogenic stimulus. The cells subsequently proliferate and differentiate to form endothelial tubes and capillary-like structures. Little is known about the metabolic adaptation of endothelial cells through such a transformation. We studied the metabolic changes of endothelial cell activation by growth factors using human umbilical vein endothelial… CONTINUE READING

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