Characterization of the meningococcal DNA glycosylase Fpg involved in base excision repair

Abstract

Neisseria meningitidis, the causative agent of meningococcal disease, is exposed to high levels of reactive oxygen species inside its exclusive human host. The DNA glycosylase Fpg of the base excision repair pathway (BER) is a central player in the correction of oxidative DNA damage. This study aimed at characterizing the meningococcal Fpg and its role in… (More)
DOI: 10.1186/1471-2180-9-7

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