Characterization of the measurement error structure in 1D 1H NMR data for metabolomics studies.

@article{Karakach2009CharacterizationOT,
  title={Characterization of the measurement error structure in 1D 1H NMR data for metabolomics studies.},
  author={Tobias K. Karakach and Peter D. Wentzell and John A. Walter},
  journal={Analytica chimica acta},
  year={2009},
  volume={636 2},
  pages={163-74}
}
NMR-based metabolomics is characterized by high throughput measurements of the signal intensities of complex mixtures of metabolites in biological samples by assaying, typically, bio-fluids or tissue homogenates. The ultimate goal is to obtain relevant biological information regarding the dissimilarity in patho-physiological conditions that the samples experience. For a long time now, this information has been obtained through the analysis of measured NMR signals via multivariate statistics… CONTINUE READING
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