Characterization of the measurement error structure in 1D 1H NMR data for metabolomics studies.

  title={Characterization of the measurement error structure in 1D 1H NMR data for metabolomics studies.},
  author={Tobias K. Karakach and Peter D. Wentzell and John A. Walter},
  journal={Analytica chimica acta},
  volume={636 2},
NMR-based metabolomics is characterized by high throughput measurements of the signal intensities of complex mixtures of metabolites in biological samples by assaying, typically, bio-fluids or tissue homogenates. The ultimate goal is to obtain relevant biological information regarding the dissimilarity in patho-physiological conditions that the samples experience. For a long time now, this information has been obtained through the analysis of measured NMR signals via multivariate statistics… CONTINUE READING
6 Citations
5 References
Similar Papers


Publications referenced by this paper.
Showing 1-5 of 5 references


  • P. D. Wentzell, T. D. Andrews, D. C. Hamilton, B. Kowalski
  • Chemom. 11
  • 1997
Highly Influential
9 Excerpts


  • P. Paatero, P. K. Hopke
  • Chim. Acta 490
  • 2003


  • J. Nicholson, J. Connelly, J. C. Lindon, E. Holmes
  • Rev. Drug Discov. 1
  • 2002
1 Excerpt


  • J. Nicholson, J. C. Lindon
  • Holmes, Xenobiotica 29
  • 1999
1 Excerpt


  • E. Holmes, J. Nicholson, +4 authors J. Connelly
  • Intell. Lab. Syst. 44
  • 1998
1 Excerpt

Similar Papers

Loading similar papers…