Characterization of the mammalian family of DCN-type NEDD8 E3 ligases

Abstract

Cullin-RING ligases (CRL) are ubiquitin E3 enzymes that bind substrates through variable substrate receptor proteins and are activated by attachment of the ubiquitin-like protein NEDD8 to the cullin subunit. DCNs are NEDD8 E3 ligases that promote neddylation. Mammalian cells express five DCN-like (DCNL) proteins but little is known about their specific… (More)
DOI: 10.1242/jcs.181784

Topics

Cite this paper

@inproceedings{Keuss2016CharacterizationOT, title={Characterization of the mammalian family of DCN-type NEDD8 E3 ligases}, author={Matthew J. Keuss and Yann Thomas and Robin Mcarthur and Nicola T. Wood and Axel Knebel and Thimo Kurz}, booktitle={Journal of cell science}, year={2016} }