Characterization of the major heparan sulfate proteoglycan secreted by bovine aortic endothelial cells in culture. Homology to the large molecular weight molecule of basement membranes.

@article{Saku1989CharacterizationOT,
  title={Characterization of the major heparan sulfate proteoglycan secreted by bovine aortic endothelial cells in culture. Homology to the large molecular weight molecule of basement membranes.},
  author={Takashi Saku and Heinz Furthmayr},
  journal={The Journal of biological chemistry},
  year={1989},
  volume={264 6},
  pages={3514-23}
}
To determine the precise architecture and functional characteristics of the subendothelial basal lamina, detailed information of the molecules contained in this structure is required. To this end, we have studied low passage bovine aortic endothelial cells and have isolated the major heparan sulfate-containing proteoglycan from the growth medium of the cells maintained under static culture conditions. This large macromolecule consists of a core protein approximately 500,000 daltons in mass and… CONTINUE READING
27 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

Similar Papers

Loading similar papers…