Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli.

@article{Henry1994CharacterizationOT,
  title={Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli.},
  author={Lynda Henry and Donglan Xia and Marisa Wilke and Johann Deisenhofer and Robert D. Gerard},
  journal={Journal of virology},
  year={1994},
  volume={68 8},
  pages={5239-46}
}
The adenovirus fiber protein is used for attachment of the virus to a specific receptor on the cell surface. Structurally, the protein consists of a long, thin shaft that protrudes from the vertex of the virus capsid and terminates in a globular domain termed the knob. To verify that the knob is the domain which interacts with the cellular receptor, we have… CONTINUE READING