Characterization of the isocitrate lyase gene from Corynebacterium glutamicum and biochemical analysis of the enzyme.

@article{Reinscheid1994CharacterizationOT,
  title={Characterization of the isocitrate lyase gene from Corynebacterium glutamicum and biochemical analysis of the enzyme.},
  author={Dieter J Reinscheid and Bernhard J Eikmanns and Hermann 4 Sahm},
  journal={Journal of bacteriology},
  year={1994},
  volume={176 12},
  pages={3474-83}
}
Isocitrate lyase is a key enzyme in the glyoxylate cycle and is essential as an anaplerotic enzyme for growth on acetate as a carbon source. It is assumed to be of major importance in carbon flux control in the amino acid-producing organism Corynebacterium glutamicum. In crude extracts of C. glutamicum, the specific activities of isocitrate lyase were found to be 0.01 U/mg of protein after growth on glucose and 2.8 U/mg of protein after growth on acetate, indicating tight regulation. The… CONTINUE READING
33 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

Similar Papers

Loading similar papers…