Characterization of the interface between adsorbed fibronectin and human embryonic stem cells.

@article{Kalaskar2013CharacterizationOT,
  title={Characterization of the interface between adsorbed fibronectin and human embryonic stem cells.},
  author={Deepak Kalaskar and Joan E Downes and Patricia Murray and David H. Edgar and Rachel L Williams},
  journal={Journal of the Royal Society, Interface},
  year={2013},
  volume={10 83},
  pages={20130139}
}
The cell-substrate interface plays a key role in the regulation of cell behaviour. Defining the properties of this interface is particularly important for human embryonic stem (hES) cell culture, because changes in this environment can regulate hES cell differentiation. It has been established that fibronectin-coated surfaces can promote the attachment, growth and maintenance of the undifferentiated phenotype of hES cells. We investigated the influence of the surface density of adsorbed… CONTINUE READING

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