Characterization of the interactions among vaccinia virus transcription factors G2R, A18R, and H5R.

@article{Black1998CharacterizationOT,
  title={Characterization of the interactions among vaccinia virus transcription factors G2R, A18R, and H5R.},
  author={Esther P. Black and Nissin Moussatch{\'e} and Richard C. Condit},
  journal={Virology},
  year={1998},
  volume={245 2},
  pages={313-22}
}
Prior genetic analysis suggests that there may exist an interaction between the products of the vaccinia virus genes A18R, a putative negative transcription elongation factor, and G2R, a putative positive transcription elongation factor. In addition, affinity purification of polyhistidine-tagged G2R protein overexpressed in vaccinia virus-infected cells, reported here, results in copurification of the vaccinia H5R protein, previously characterized as a late viral transcription factor. We have… CONTINUE READING

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