Characterization of the interaction between galectin-1 and lymphocyte glycoproteins CD45 and Thy-1.

@article{Symons2000CharacterizationOT,
  title={Characterization of the interaction between galectin-1 and lymphocyte glycoproteins CD45 and Thy-1.},
  author={Antony Symons and Douglas N. W. Cooper and A. Neil Barclay},
  journal={Glycobiology},
  year={2000},
  volume={10 6},
  pages={559-63}
}
Galectin-1 is a sugar binding protein specific for beta-galactosides and not requiring metal ions for binding activity. It exists as a soluble protein which forms a noncovalent homodimer and is expressed with a broad tissue distribution. Recently, galectin-1 has been shown to play a possible role in the immune system mediating apoptosis of activated T cells with indirect evidence suggesting that galectin-1 interacts with the heavily glycosylated, transmembrane, protein phosphotyrosine… CONTINUE READING
18 Citations
31 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 31 references

Apoptosis of T

  • N. L. Perillo, K. E. Pace, J. J. Seilhamer, L. G. Baum
  • 1995
Highly Influential
6 Excerpts

Similar Papers

Loading similar papers…