Characterization of the insulin-like growth factor axis and Wilms' tumour suppressor gene in hyperparathyroidism.


BACKGROUND Genetic mutations and upregulation of growth factors are implicated in the pathogenesis of hyperparathyroidism. The aim of this study was to evaluate the role of Wilms' tumour suppressor gene (WT-1) and the insulin-like growth factor (IGF) axis in hyperparathyroidism. METHODS The expression of WT-1 and IGF components was examined by… (More)


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