Characterization of the inflammatory response induced by corneal infection with Pseudomonas aeruginosa.

@article{Kernacki1994CharacterizationOT,
  title={Characterization of the inflammatory response induced by corneal infection with Pseudomonas aeruginosa.},
  author={Karen A. Kernacki and Richard S. Berk},
  journal={Journal of ocular pharmacology},
  year={1994},
  volume={10 1},
  pages={281-8}
}
In order to characterize the inflammatory response to corneal infection by Pseudomonas aeruginosa, ocular cytokine and arachidonic acid metabolite levels were determined in the C57BL/6J strain of mice. The effects of topical anti-inflammatory drugs on the ability of the mice to clear viable P. aeruginosa from the eyes during the 12 day infection period was also examined. Ocular IL-1 alpha, IL-6, and TNF-alpha were detected over an 11 day time period. Little or no bacteria, as determined by… CONTINUE READING