Characterization of the immune response induced by pertussis OMVs-based vaccine.

@article{Bottero2016CharacterizationOT,
  title={Characterization of the immune response induced by pertussis OMVs-based vaccine.},
  author={Daniela Bottero and Mar{\'i}a Emilia Gaillard and Eugenia Zurita and Griselda N. Moreno and Dominique Martinez and Erika Bartel and Stefania Bravo and Francisco Carriquiriborde and Agustina J. Errea and Celina E Castuma and Mart{\'i}n Rumbo and Daniela Flavia Hozbor},
  journal={Vaccine},
  year={2016},
  volume={34 28},
  pages={3303-9}
}
For the development of a third generation of pertussis vaccine that could improve the control of the disease, it was proposed that the immune responses induced by the classic whole cell vaccine (wP) or after infection should be used as a reference point. We have recently identified a vaccine candidate based on outer membrane vesicles (OMVs) derived from the disease etiologic agent that have been shown to be safe and protective in mice model of infection. Here we characterized OMVs-mediated… CONTINUE READING
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