Characterization of the immune response against hepatitis C infection in recovered, and chronically infected chimpanzees.

@article{Shata2002CharacterizationOT,
  title={Characterization of the immune response against hepatitis C infection in recovered, and chronically infected chimpanzees.},
  author={Mohamed Tarek M. Shata and Donald D. Anthony and Nicole L Carlson and Linda Andrus and Betsy Brotman and Nancy Tricoche and Patricia McCormack and Alfred M. Prince},
  journal={Journal of viral hepatitis},
  year={2002},
  volume={9 6},
  pages={400-10}
}
The immune response to hepatitis C virus (HCV) is believed to be critical in determining the outcome of the disease. In this study we have analysed epitope recognition, cytokine profile, and anti-HCV antibody responses in chronically HCV-infected and recovered chimpanzees. Quantitative measurement of anti-HCV antibody in HCV-infected chimpanzees revealed that the response in HCV- recovered chimpanzees peaked within 4-20 weeks. In contrast, the anti-HCV antibody responses in chronically HCV… CONTINUE READING