Characterization of the immediate-early functions of pseudorabies virus.

  title={Characterization of the immediate-early functions of pseudorabies virus.},
  author={Seiji Ihara and Laurie Feldman and Shinji Watanabe and TAMAR BEN-PORAT},
  volume={131 2},
The immediate-early transcripts of pseudorabies virus have been located in a region of the genome situated internally within the inverted repeat between map positions 0.99 and 0.95. A single immediate-early transcript (approximately 6 kb) can be detected both in the cytoplasmic and nuclear fractions of infected, cycloheximide-treated cells. Analysis of the proteins synthesized after removal of cycloheximide from infected cells or after translation in vitro of the RNA isolated from these cells… CONTINUE READING