Characterization of the human rod transducin alpha-subunit gene.

  title={Characterization of the human rod transducin alpha-subunit gene.},
  author={S L Fong},
  journal={Nucleic acids research},
  volume={20 11},
The human rod transducin alpha subunit (Tr alpha) gene has been cloned. A cDNA clone, HG14, contained a 1.1 kb insertion when compared with the human Tr alpha cDNA published by Van Dop et al. (1). Based on two overlapping clones isolated from a human genomic library, the human Tr alpha gene is 4.9 kb in length and consists of nine exons interrupted by eight introns. Northern blots of human retina total RNA showed that the gene is transcribed by rod photoreceptors into two species of mRNA, 1.3… CONTINUE READING