Characterization of the human forkhead gene FREAC-4. Evidence for regulation by Wilms' tumor suppressor gene (WT-1) and p53.

@article{Ernstsson1996CharacterizationOT,
  title={Characterization of the human forkhead gene FREAC-4. Evidence for regulation by Wilms' tumor suppressor gene (WT-1) and p53.},
  author={S Ernstsson and Stefan Pierrou and Malin Hulander and Anna Cederberg and Matti Hellqvist and Peter Carlsson and Sven Enerb{\"a}ck},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 35},
  pages={21094-9}
}
We describe the cloning and sequence analysis of a nearly full-length cDNA as well as a corresponding 5.2-kilobase pair genomic fragment encoding FREAC-4, a member of the forkhead family of transcription factors. The cDNA is collinear with respect to the coding region of the intronless genomic clone. The conceptual translation product predicts a protein of 465 amino acids with a hyperacidic amino-terminal end, a DNA binding forkhead domain and a carboxyl-terminal part that is rich in… CONTINUE READING