Characterization of the human EPLIN (Epithelial Protein Lost in Neoplasm) gene reveals distinct promoters for the two EPLIN isoforms.

@article{Chen2000CharacterizationOT,
  title={Characterization of the human EPLIN (Epithelial Protein Lost in Neoplasm) gene reveals distinct promoters for the two EPLIN isoforms.},
  author={Steve T Chen and Raymond Scott Maul and Hong Rye Kim and David D. Chang},
  journal={Gene},
  year={2000},
  volume={248 1-2},
  pages={69-76}
}
EPLIN is a novel LIM domain protein that co-localizes to the actin stress fibers and focal adhesion plaques. We previously have demonstrated that two isoforms, the 600aa EPLIN-alpha and the 759aa EPLIN-beta, are generated from a single gene. In the majority of human breast and prostate cancer cell lines, the expression of EPLIN-alpha is significantly… CONTINUE READING