Characterization of the heme binding properties of Staphylococcus aureus IsdA.

@article{Vermeiren2006CharacterizationOT,
  title={Characterization of the heme binding properties of Staphylococcus aureus IsdA.},
  author={Christie L Vermeiren and Mark Pluym and John Mack and David E Heinrichs and Martin J. Stillman},
  journal={Biochemistry},
  year={2006},
  volume={45 42},
  pages={12867-75}
}
We report the first characterization of the physical and spectroscopic properties of the Staphylococcus aureus heme-binding protein IsdA. In this study, a combination of gel filtration chromatography and analytical centrifugation experiments demonstrate that IsdA, in solution, is a monomer and adopts an extended conformation that would suggest that it has… CONTINUE READING