Characterization of the glutamatergic system for induction and maintenance of allodynia

@article{Minami2001CharacterizationOT,
  title={Characterization of the glutamatergic system for induction and maintenance of allodynia},
  author={T. Minami and S. Matsumura and E. Okuda-Ashitaka and K. Shimamoto and S. Ito},
  journal={Brain Research},
  year={2001},
  volume={895},
  pages={178-185}
}
  • T. Minami, S. Matsumura, +2 authors S. Ito
  • Published 2001
  • Chemistry, Medicine
  • Brain Research
  • Glutamate is the main excitatory neurotransmitter in the central nervous system and has been shown to be involved in spinal nociceptive processing. We previously demonstrated that intrathecal (i.t.) administration of prostaglandin (PG) E(2) and PGF(2 alpha) induced touch-evoked pain (allodynia) through the glutamatergic system by different mechanisms. In the present study, we characterized glutamate receptor subtypes and glutamate transporters involved in induction and maintenance of PGE(2… CONTINUE READING
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