Characterization of the genomic structure of the human vitamin C transporter SVCT1 (SLC23A2).

@article{Erichsen2001CharacterizationOT,
  title={Characterization of the genomic structure of the human vitamin C transporter SVCT1 (SLC23A2).},
  author={Hans Christian Erichsen and Peter Eck and Mark Levine and Stephen K Chanock},
  journal={The Journal of nutrition},
  year={2001},
  volume={131 10},
  pages={2623-7}
}
Vitamin C (L-ascorbic acid), a critical cofactor for intracellular enzymatic reactions, functions as a scavenger of free oxygen radicals and is an essential micronutrient. Vitamin C is actively transported into cells by one of two closely related sodium-dependent transporters, SVCT1 or SVCT2. In this paper, we report the complete sequencing and gene structure of SLC23A2, the gene encoding SVCT1. The1797-bp cDNA sequence (open reading frame) of the SLC23A2 gene was derived from a compact genomic… CONTINUE READING
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