Characterization of the genomic organization of human carcinoembryonic antigen (CEA): comparison with other family members and sequence analysis of 5' controlling region.

@article{Willcocks1990CharacterizationOT,
  title={Characterization of the genomic organization of human carcinoembryonic antigen (CEA): comparison with other family members and sequence analysis of 5' controlling region.},
  author={Teresa C. Willcocks and Ian W. Craig},
  journal={Genomics},
  year={1990},
  volume={8 3},
  pages={492-500}
}
A cosmid containing the entire coding region for human carcinoembryonic antigen has been isolated. Detailed analysis and sequencing have determined an organization comprising nine exons encoding amino acids and one for a 3' untranslated fragment. Comparison with other family members reveals a complex pattern of homology at the 3' end of the gene. The 5… CONTINUE READING