Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast

@inproceedings{Natrajan2014CharacterizationOT,
  title={Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast},
  author={Rachael Natrajan and Paul M. Wilkerson and Caterina Marchi{\`o} and Salvatore Piscuoglio and Charlotte K Y Ng and P Tjong Yoe Wai and Maryou B. K. Lambros and Eleftherios Pierre Samartzis and Konstantin Johannes Dedes and Jessica R. Frankum and Ilirjana Bajrami and A Dianne Kopec and Alan Mackay and Roger P A'hern and Kerry Fenwick and Iwanka Kozarewa and Jarle Hakas and Costas Mitsopoulos and David Hardisson and Christopher J Lord and Chandan Kumar-Sinha and Alan Ashworth and Britta Weigelt and Anna Sapino and Arul M. Chinnaiyan and Christopher A. Maher and Jorge S Reis-Filho},
  booktitle={The Journal of pathology},
  year={2014}
}
Micropapillary carcinoma (MPC) is a rare histological special type of breast cancer, characterized by an aggressive clinical behaviour and a pattern of copy number aberrations (CNAs) distinct from that of grade- and oestrogen receptor (ER)-matched invasive carcinomas of no special type (IC-NSTs). The aims of this study were to determine whether MPCs are underpinned by a recurrent fusion gene(s) or mutations in 273 genes recurrently mutated in breast cancer. Sixteen MPCs were subjected to… CONTINUE READING