Characterization of the generation of radiolabeled monodisperse albuterol particles using the spinning-top aerosol generator.

Abstract

UNLABELLED Inhaled radiolabeled aerosols provide invaluable information about in vivo drug deposition. Here, we report our methodology for radiolabeling and imaging monodisperse pharmacologic aerosols in order to study basic aerosol science concepts of drug delivery within the human airways. METHODS We used a spinning-top aerosol generator to produce (99m… (More)

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