Characterization of the functional domain of major surface protein 1a involved in adhesion of the rickettsia Anaplasma marginale to host cells.

@article{Fuente2003CharacterizationOT,
  title={Characterization of the functional domain of major surface protein 1a involved in adhesion of the rickettsia Anaplasma marginale to host cells.},
  author={Jos{\'e} de la Fuente and Jose Carlos Garcia-Garcia and Edmour F. Blouin and Katherine M. Kocan},
  journal={Veterinary microbiology},
  year={2003},
  volume={91 2-3},
  pages={265-83}
}
The major surface protein (MSP) 1a of the genus type species Anaplasma marginale (Rickettsiales: Anaplasmataceae) has been shown to mediate adhesion, infection and transmission of the organism, as well as to contribute to protective immunity in cattle. MSP1a contains a variable number of tandemly repeated peptides in the amino-terminal region, while the remainder of the protein is highly conserved among isolates. The number of repeats varies among geographic isolates of A. marginale but is… CONTINUE READING