Characterization of the exon structure of the polycystic kidney disease 2 gene (PKD2).

Abstract

PKD2, the gene defective in the second form of autosomal dominant polycystic kidney disease (ADPKD), has been identified by positional cloning and found to encode an integral membrane protein with similarity to the gene for the more common form of ADPKD and to calcium channels. We have determined the exon-intron structure of the PKD2 gene. PKD2 is encoded… (More)

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@article{Hayashi1997CharacterizationOT, title={Characterization of the exon structure of the polycystic kidney disease 2 gene (PKD2).}, author={Toshiaki Hayashi and Tsutomu Mochizuki and David M. Reynolds and G Wu and Y. S. Cai and Stefan Somlo}, journal={Genomics}, year={1997}, volume={44 1}, pages={131-6} }