• Corpus ID: 15485874

Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature.

@article{Kong2001CharacterizationOT,
  title={Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature.},
  author={Garheng Kong and Rod D. Braun and Mark W. Dewhirst},
  journal={Cancer research},
  year={2001},
  volume={61 7},
  pages={
          3027-32
        }
}
The efficacy of novel cancer therapeutics can be hampered by inefficient delivery of agents to the tumor at effective concentrations. Liposomes have been used as a method to overcome some delivery issues and, in combination with hyperthermia, have been shown to increase drug delivery to tumors. This study investigates the effects of a range of temperatures (34-42 degrees C) and hyperthermia treatment scheduling (time between hyperthermia and drug administration as well as between consecutive… 

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