Characterization of the chromosomal translocation t(10;17)(q22;p13) in clear cell sarcoma of kidney.

  title={Characterization of the chromosomal translocation t(10;17)(q22;p13) in clear cell sarcoma of kidney.},
  author={Elaine O'Meara and Deirdre Stack and Cheng-Han Lee and Abbott Julian Garvin and Thomas Morris and Pedram Argani and Jeong Sam Han and Jenny Karlsson and David Gisselson and Ivo Leuschner and Manfred Gessler and Norbert Graf and Jonathan Alfred Fletcher and M J O'sullivan},
  journal={The Journal of pathology},
  volume={227 1},
Clear cell sarcoma of kidney (CCSK) is classified as a tumour of unfavourable histology by the National Wilms' Tumor Study Group. It has worse clinical outcomes than Wilms' tumour. Virtually nothing is known about CCSK biology, as there have been very few genetic aberrations identified to act as pointers in this cancer. Three cases of CCSK bearing a chromosomal translocation, t(10;17)(q22;p13), have been individually reported but not further investigated to date. The aim of this research was to… CONTINUE READING
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