Characterization of the budding compartment of mouse hepatitis virus: evidence that transport from the RER to the Golgi complex requires only one vesicular transport step

@article{KrijnseLocker1994CharacterizationOT,
  title={Characterization of the budding compartment of mouse hepatitis virus: evidence that transport from the RER to the Golgi complex requires only one vesicular transport step},
  author={J Krijnse-Locker and Maria Ericsson and Peter J. M. Rottier and Gareth Griffiths},
  journal={The Journal of Cell Biology},
  year={1994},
  volume={124},
  pages={55 - 70}
}
Mouse hepatitis coronavirus (MHV) buds into pleomorphic membrane structures with features expected of the intermediate compartment between the ER and the Golgi complex. Here, we characterize the MHV budding compartment in more detail in mouse L cells using streptolysin O (SLO) permeabilization which allowed us to better visualize the membrane structures at the ER-Golgi boundary. The MHV budding compartment shares membrane continuities with the rough ER as well as with cisternal elements on one… CONTINUE READING

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