Characterization of the biological processes shaping the genetic structure of the Italian population
@article{Parolo2015CharacterizationOT, title={Characterization of the biological processes shaping the genetic structure of the Italian population}, author={Silvia Parolo and A. Lisa and D. Gentilini and A. D. Di Blasio and S. Barlera and E. Nicolis and G. Boncoraglio and E. Parati and S. Bione}, journal={BMC Genetics}, year={2015}, volume={16} }
BackgroundThe genetic structure of human populations is the outcome of the combined action of different processes such as demographic dynamics and natural selection. Several efforts toward the characterization of population genetic architectures and the identification of adaptation signatures were recently made. In this study, we provide a genome-wide depiction of the Italian population structure and the analysis of the major determinants of the current existing genetic variation.ResultsWe… CONTINUE READING
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References
SHOWING 1-10 OF 78 REFERENCES
Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human Evolution
- Biology, Medicine
- PLoS genetics
- 2011
- 417
- PDF
An Overview of the Genetic Structure within the Italian Population from Genome-Wide Data
- Medicine, Biology
- PloS one
- 2012
- 41
- PDF
Investigation of the fine structure of European populations with applications to disease association studies
- Biology, Medicine
- European Journal of Human Genetics
- 2008
- 173
- PDF
Correlation between Genetic and Geographic Structure in Europe
- Biology, Geography
- Current Biology
- 2008
- 453
- PDF
Geographical structure and differential natural selection among North European populations.
- Biology, Medicine
- Genome research
- 2009
- 112
- PDF
Signals of recent positive selection in a worldwide sample of human populations.
- Biology, Medicine
- Genome research
- 2009
- 673
- PDF
Human genome variability, natural selection and infectious diseases.
- Biology, Medicine
- Current opinion in immunology
- 2014
- 52
Identification and Analysis of Genomic Regions with Large Between‐Population Differentiation in Humans
- Biology, Medicine
- Annals of human genetics
- 2008
- 80