Characterization of the binding of human growth hormone to microsomal membranes from rat liver.

@article{Herington1976CharacterizationOT,
  title={Characterization of the binding of human growth hormone to microsomal membranes from rat liver.},
  author={Adrian C. Herington and N M Veith and H. G. Burger},
  journal={The Biochemical journal},
  year={1976},
  volume={158 1},
  pages={61-9}
}
The binding of 125I-labelled human growth hormone to the 100000g microsomal membrane fraction prepared from the livers of normal female rats was dependent on time, temperature, pH, membrane concentration and concentration of 125I-labelled human growth hormone. At 22 degrees C binding reached a steady state after 16h, with the mean maximal specific binding… CONTINUE READING