Characterization of the autoimmune response against the nerve tissue S100β in patients with type 1 diabetes.


Type 1 diabetes results from destruction of insulin-producing beta cells in pancreatic islets and is characterized by islet cell autoimmunity. Autoreactivity against non-beta cell-specific antigens has also been reported, including targeting of the calcium-binding protein S100β. In preclinical models, reactivity of this type is a key component of the early… (More)
DOI: 10.1111/cei.12572


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