Characterization of the attachment of Treponema pallidum (Nichols strain) to cultured mammalian cells and the potential relationship of attachment to pathogenicity.

@article{Fitzgerald1977CharacterizationOT,
  title={Characterization of the attachment of Treponema pallidum (Nichols strain) to cultured mammalian cells and the potential relationship of attachment to pathogenicity.},
  author={Thomas J. Fitzgerald and R. Colin Johnson and James N. Miller and J. A. C. Sykes},
  journal={Infection and immunity},
  year={1977},
  volume={18 2},
  pages={467-78}
}
The interaction of Treponema pallidum (Nichols strain) with 19 different cultured mammalian cell types was examined. These types included cells derived from testis, kidney, spleen, lung, epidermis, cervix, urethra, and nerve tissue of human, rabbit, or rat origins. They represented normal and malignant cells, epithelial and fibroblastic morphology, cell lines, and cell strains, Large numbers of organisms attached to the cultured cells; this attachment prolonged the time of retention of active… CONTINUE READING

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Tissue culture and Treponema pallidum

  • T. J. Fitzgerald, J. N. Miller, J. A. Sykes, R. C. Johnson
  • 1976

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